Praluent — New Cholesterol Drug Linked To Neurological Risks

| June 25, 2015

Earlier this year, the pharmaceutical giant Sanofi submitted its application to the European Medicines Agency (EMA) and the American Food and Drug Administration (FDA) for the approval of a new cholesterol-lowering drug, Praluent (alirocumab).

Praluent is an injectable drug that falls in a class of drug known as PCSK9 inhibitors. It is intended for the treatment of patients with hypercholesterolemia — people with hereditary high cholesterol. PCSK9 promises to reduce LDL cholesterol levels to previously unheard of lows… dangerously low levels!

Shortly after Sanofi submitted Praluent’s application for approval, the first thing the FDA said was that it was concerned about the neurocognitive side effects these drugs have shown.

That’s right, PCSK9 inhibitors damage your brain.

In fact, the FDA was so concerned about the detrimental effect these drugs can have on your brain that it asked Sanofi to show neurocognitive testing in outcome trials. In other words, the drug maker needs to show that Praluent won’t fry your brain.

Why is there this risk?

As we’ve mentioned before cholesterol is found in every cell of your body and that includes your brain, which mainly consists of fat and cholesterol and plays a vital role in neurological function.

Suffice to say, lowering your cholesterol levels to the ridiculously low government recommended levels is extremely risky. And it should come as no surprise that cholesterol-lowering statin drugs have been linked to memory loss, depression and even dementia… in middle-aged patients!

When taking a statin drug, people are usually able to reduce their cholesterol to between 70 and 100 mg/dL. However, patients with hypercholesterolemia usually cannot reach the ridiculously low targets set by the mainstream and that’s where PCSK9 inhibitors come into the picture.

According to Dr. Elliott Antman, president-elect of the American Heart Association and a dean at Harvard Medical School, PCSK9 inhibitors can reduce cholesterol levels to below 50 mg/dL.

That’s just madness!

However, now it seems that all those neurological risks associated with Praluent have been swept under the carpet and the FDA is carrying on full steam ahead with the approval of this brain toaster of a drug.

Earlier this month, an FDA advisory panel voted 13-3 in favour of Praluent’s approval. However, the panellists said they would like to see follow-up data on a number of other potential side effects suggested by shorter studies, including cognitive problems, allergic reactions and diabetes.

But here’s the part that really concerns me: A number of panellists said the drug should only be used in patients with abnormally high cholesterol levels caused by an inherited disorder — familial hypercholesterolemia.

So, hang on a bit… Praluent was initially designed to ONLY be given to patients with familial hypercholesterolemia. Now it looks like the drug is set to be let loose on the entire population… and of course it would be because analysts expect PCSK9 drugs to grow into blockbuster medicines, generating tens of billions in new sales.

As always, it’s all about the money.

Never mind the fact that PCSK9 drugs can (and probably will) fry your brain or that some of the FDA’s own panel members doubt whether these drugs actually reduce heart problems, the stage is set for Praluent to be rolled out to millions of patients who will either be forced by their doctors to take this drug or who have been scared into becoming so cholesterol-phobic that they will do anything to lower their levels… at the cost of their own health.

As a sufferer of hypercholesterolemia, I stopped taking statin drugs after suffering with terrible side effects and I now even refuse to discuss cholesterol with my doctor. He doesn’t like it, but that’s his problem.

Despite my doctor’s fear-mongering and warnings of an early death, I live a very healthy and active life at the age of 40… no thanks to statin drugs. So, there is no way in hell that anyone will ever see me anywhere near PCSK9 inhibitors.

Here's to keeping your heart strong and healthy

Francois Lubbe
Editor
for The Cholesterol Truth



If you enjoyed this content or found it useful and educational, please share this article with your friends and family.



Bear in mind we are not addressing anyone’s personal situation and you should rely on this for informational purposes only. Please consult with your own physician before acting on any recommendations contained herein.


Sources:

Arteriosclerosis, Thrombosis, and Vascular Biology June 30, 2008

New Cholesterol Drug PCSK9 Is Likely to Prematurely Kill You, published online 03.06.13, articles.mercola.com

Could THIS Be the Hidden Factor Behind Obesity, Heart Disease, and Chronic Fatigue?, published online 17.09.11

Praluent (anti-PCSK9), published online, consensus.druganalyst.com

New drug drastically lowers LDL cholesterol levels, stroke and heart attack risks, published online 17.03.15, ibtimes.co.uk

FDA advised by expert panel to approve highly anticipated cholesterol drug, published online 09.06.15, theguardian.com

Print Friendly

Tags: , , , ,

Category: Latest Cholesterol Research

Comments (1)

Testimonials are based on the personal experience of individuals. Results are not typical and the potential benefits of taking any drug or supplement may vary depending on your individual needs and health requirements. Please consult your GP before making any changes to your medical regimen.

  1. Christine says:

    I have just had my second injection of parulent I am suffering severe hair loss. I am on anti depressants and the depression has increased in the past two weeks. I have experienced debilitating muscle pain.
    These symptoms have manifested over two weeks God only knows what is lurking in the next ten weeks of trial of this drug.

Don't Forget Your Free Blood Pressure Report...

Just RSVP below for immediate access to this valuable report, with our sincere compliments.

As you'll discover in your FREE report, there are safe, natural ways to protect your heart without the use of risky, side-effect-ridden drugs.

And that's not all. When you enter your email address, you'll also receive the Daily Health e-letter. Each day in the Daily Health, you'll get:

• News on the latest cutting-edge natural health breakthroughs.
• The truth behind mainstream health headlines
• First access to new product releases
• And much, much more!

Enter your email address below to receive your FREE report, 10 Drug-Free Ways to Lower High Blood Pressure and Protect Against a Heart Attack or Stroke. We'll deliver it straight to your inbox in a matter of minutes.

10 Drug-Free Ways to Lower High Blood Pressure and Protect Against a Heart Attack or Stroke

Just RSVP below for immediate access to this valuable report, with our sincere compliments.

As you'll discover in your FREE report, there are safe, natural ways to protect your heart without the use of risky, side-effect-ridden drugs.

And that's not all. When you enter your email address, you'll also receive the Daily Health e-letter. Each day in the Daily Health, you'll get:

• News on the latest cutting-edge natural health breakthroughs.
• The truth behind mainstream health headlines
• First access to new product releases
• And much, much more!

Enter your email address below to receive your FREE report, 10 Drug-Free Ways to Lower High Blood Pressure and Protect Against a Heart Attack or Stroke. We'll deliver it straight to your inbox in a matter of minutes.