Tag: "good cholesterol"

Evidence Turns Common Cholesterol Assumptions On Their Head

| August 18, 2014 | Comments (2)

Cholesterol in the bloodstream is carried within protein-rich packages known as ‘lipoproteins’. These come in two main types, so-called ‘low-density lipoprotein-cholesterol’ (LDL-C) and ‘high-density lipoprotein-cholesterol’ (HDL-C). Conventional wisdom has it that LDL-C is responsible for dumping cholesterol on the inside of arteries, and is dubbed ‘bad cholesterol’ as a result. On the other hand, HDL-cholesterol […]

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Low LDL Cholesterol Levels Linked To Higher Mortality Rate

| January 31, 2014 | Comments (0)

A new study has linked too low LDL cholesterol levels with an increased risk of mortality… From a purely physiological perspective, the heart is essentially a bag of muscle that pumps blood around the body. In certain circumstances, the heart can be weak and the pumping action inefficient. This situation, generally referred to as ‘heart […]

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Cholesterol: Lower Is Not Always Better

| December 27, 2012 | Comments (2)

When we hear the word ‘cholesterol’ it’s easy to imagine this fat-like substance whooshing around in the bloodstream and perhaps contributing to the build-up of ‘atherosclerotic plaque’ on the inside of artery walls. However, we should perhaps not forget that this substance is an essential body constituent and, for example, is a basic building block within […]

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Fibrates: Cholesterol-Modifying Drug Bites The Dust

| December 13, 2012 | Comments (0)

The medical research community seems to have an unending capacity to churn out research which appears to support the ‘cholesterol hypothesis’ and the use of cholesterol-lowering drugs. This time fibrates enjoys a bit of the limelight. A favourite tactic here is to express any benefits as a relative reduction in risk. This way of expressing […]

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Fibrates Have Little Impact Preventing Cardiovascular Events

| December 6, 2012 | Comments (0)

Statins are the most commonly-prescribed type of drugs used to treat ‘high cholesterol’, but doctors have other weapons in their supposed armoury here, including what are known as ‘fibrates’. This class of drugs, which includes the drugs clofibrate, gemfibrozil and fenofibrate, works mainly to lower levels of ‘unhealthy’ blood fats known as triglycerides, while raising […]

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Mipomersen – New Cholesterol Drug, New Side Effects

| November 5, 2012 | Comments (1)

I was reading here that the Food and Drug Administration in the US has approved a new drug to treat raised cholesterol. It goes by the name of mipomersen, and will specifically be used for the treatment of ‘homozygous familial hypercholesterolaemia’ – a severe form of genetically driven raised cholesterol levels. The drug, taken by […]

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Biases Clouding Statin Drug Trials

| October 19, 2012 | Comments (1)

The case for the benefits of statins is built on data coming from what are termed ‘randomised controlled trials’.  These are often referred to as the ‘gold standard’ tests of any treatment. In such studies, normally half of a group of people are randomly assigned to take a statin, while the other half gets a […]

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Saturated Fat Not The Villain It’s Made Out To Be

| October 3, 2012 | Comments (0)

When it comes to nutritional approaches to preventing heart disease, perhaps the most consistent piece of advice we’ve been given by health professionals and governments is to avoid saturated fat. This type of fat, found in foods such as meat, eggs and dairy products, is claimed to push up blood levels of cholesterol, which in […]

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